Xanax (alprazolam) typically starts to take effect within about an hour after oral ingestion, reaching peak blood concentrations in 1 to 2 hours. The noticeable sedative and calming effects usually last around 4 to 8 hours, with many sources citing about 4 hours as the duration of strong effects
. The drug's half-life-the time it takes for the body to eliminate half of the dose-averages around 11 hours but can vary widely from about 6 to 27 hours depending on individual factors like metabolism, age, liver function, and dosage
. Because it takes about 4 to 5 half-lives to clear a drug from the body, Xanax can remain detectable and active in the system for approximately 2 to 4 days in most people, though in some cases it can last up to 5 to 6 days
. In summary:
- Onset of effects: Within 1 hour
- Peak effects: 1–2 hours after taking
- Duration of noticeable effects: About 4 to 8 hours
- Half-life: Approximately 11 hours (range 6–27 hours)
- Time to clear from body: Typically 2 to 4 days, up to 5–6 days in some individuals
These durations can vary based on individual metabolism, dosage, frequency of use, and other health factors
