The recommended waiting time between COVID-19 booster doses generally depends on age, immune status, and previous vaccination history. Here are the key guidelines for the 2024–2025 COVID-19 vaccines:
- For adults aged 65 years and older, and persons aged 6 months and older with moderate or severe immunocompromise, two doses of the 2024–2025 COVID-19 vaccine are recommended, with an interval of 6 months between the first and second doses. However, the second dose can be given as early as 2 months after the first dose if needed
- For people who have already received previous COVID-19 vaccine doses, the first 2024–2025 dose should be given at least 8 weeks after the last vaccine dose, followed by a second 2024–2025 dose 6 months later (minimum 2 months interval)
- In some cases, such as planned immunosuppressive therapy or operational reasons, a minimum interval of 3 months between booster doses may be acceptable
- For initial primary series doses (not boosters), the World Health Organization recommends an 8 to 12 week interval between the first and second doses, with a general principle of 4–6 months between completion of primary series and first booster, and between booster doses
- After a COVID-19 infection, it is generally advised to wait at least 3 months before receiving a COVID-19 vaccine dose, though timing may vary based on individual circumstances
In summary, for boosters, a 6-month interval between doses is standard for most adults at higher risk, with flexibility to shorten to 2 or 3 months in specific cases. The first booster should be given at least 8 weeks after the last vaccine dose. Additional doses may be recommended based on clinical judgment and individual risk factors
