The typical dosage and frequency for Zofran (ondansetron) 4 mg oral tablets are as follows:
- For chemotherapy-related nausea and vomiting in children aged 4 to 11 years: Take 4 mg about 30 minutes before chemotherapy, then additional 4 mg doses at 4 hours and 8 hours after the first dose. After that, take 4 mg every 8 hours (three times a day) for 1 to 2 days
- For adults, a common regimen is 4 mg taken 30 minutes before chemotherapy, followed by 4 mg doses 4 and 8 hours after the first dose, then 4 mg every 8 hours for 1 to 2 days
- For post-operative nausea and vomiting, adults may be given 8 to 16 mg before surgery, but the 4 mg dose is typically given every 12 hours orally if used for prevention
- The maximum oral dose for adults is generally 24 mg per day, often divided into 3 doses of 8 mg each, but the 4 mg dose can be taken up to three times daily (every 8 hours)
In summary, the 4 mg dose of Zofran is usually taken up to three times a day, spaced about 8 hours apart, especially after the initial doses given closer together during chemotherapy or surgery
. Always follow a healthcare provider’s specific instructions for dosing. If you are using Zofran for nausea outside of chemotherapy or surgery, consult your doctor for the appropriate dosing schedule.
