Lexapro causes weight gain primarily because it increases serotonin levels in the brain, which can influence appetite, cravings, and metabolism. Specifically, the raised serotonin from Lexapro can lead to an increase in appetite and carbohydrate cravings, as well as a decrease in metabolic rate, meaning the body burns fewer calories. Additionally, mood improvements from Lexapro can result in people eating more than they did when depressed, contributing to weight gain. Other factors such as reduced physical activity from depression or anxiety symptoms and lifestyle factors like smoking or diet might also contribute to weight gain while on Lexapro.
Mechanisms Behind Lexapro-Induced Weight Gain
- Increased serotonin affects appetite and metabolism, sometimes making people hungrier and slowing calorie burning.
- Improved mood can lead to increased food intake as appetite normalizes or increases.
- Sedentary lifestyle or low energy from the underlying condition or medication effects can reduce activity levels, leading to weight gain.
- Cravings, especially for carbohydrates or sweets, may be more intense.
- Some patients may experience fluid retention or fat storage changes.
How Much Weight Gain is Typical?
Research shows about 41% of people taking Lexapro may gain weight, typically around 2.4 to 4 pounds after 6-9 months of use, although individual results vary widely.
Managing Weight Gain on Lexapro
- Monitoring diet and avoiding excessive carbohydrate or sugary food intake.
- Maintaining regular physical activity.
- Discussing any concerns with a healthcare provider for tailored advice and potential medication adjustments.
In summary, Lexapro's impact on weight is linked to its effect on serotonin levels that regulate appetite and metabolism alongside lifestyle and psychological factors.
