Sweating excessively during sleep, also known as night sweats, can happen for various reasons ranging from harmless to more serious causes. Common causes include hormonal imbalances such as menopause or thyroid disorders, certain medications like antidepressants or steroids, infections causing fever, and stress or anxiety. Environmental factors like sleeping in a warm room or wearing heavy sleepwear also contribute. Underlying conditions such as diabetes or cancer may lead to night sweats too. If night sweats are frequent, severe, or accompanied by other symptoms like unexplained weight loss or fever, it is important to consult a healthcare provider for evaluation.