Karlach loathes Gortash above all others. This is confirmed in the in-game dialogue and various player discussions, where the best answer to the question "Who does she loathe above all others?" is Gortash, with Zariel being an acceptable secondary answer
. Additionally, in Act III, when checking her bond, it is explicitly stated that she loathes Gortash
. Gortash is a character associated with cruelty and betrayal, which aligns with Karlach's backstory and motivations, as she is distrustful and hateful towards devils and those who have wronged her
