Israel Adesanya has lost to five fighters in his professional MMA career: Jan Blachowicz, Alex Pereira, Sean Strickland, Dricus Du Plessis, and Nassourdine Imavov.
- His first MMA loss was to Jan Blachowicz at UFC 259 when Adesanya moved up to light heavyweight; Blachowicz won by unanimous decision.
- He lost the UFC middleweight title to Alex Pereira by knockout at UFC 281. Pereira was his long-time rival and this was Adesanya's first finish loss in MMA.
- Sean Strickland defeated Adesanya by unanimous decision at UFC 293, taking the middleweight championship from him in a major upset.
- At UFC 305, Dricus Du Plessis submitted Adesanya with a fourth-round choke to defend his middleweight title, handing Adesanya his fourth MMA loss.
- Most recently, Nassourdine Imavov knocked out Adesanya at UFC Fight Night 250, marking Adesanya’s third consecutive loss in the octagon.
His record includes 24 wins and 5 losses in total as of early 2025.
Thus, Israel Adesanya's losses have come from these five fighters in significant bouts across middleweight and light heavyweight divisions.
