The best time to take multivitamins is with a meal that contains some dietary fat to optimize absorption of the fat-soluble vitamins (A, D, E, K). The exact time of day—morning, afternoon, or evening—depends mostly on when it is easiest for you to remember to take them consistently. Taking multivitamins with a meal also helps reduce the chance of stomach upset. Morning is a common choice since it fits well into many people's routines, but if taking multivitamins on an empty stomach causes discomfort, taking them with lunch or dinner works just as well. Some people prefer evening dosing, especially if they take other medications in the morning, although it may be harder to remember then. Ultimately, taking your multivitamin with a meal containing fat, at whatever time suits your daily routine best, is recommended. Consult a healthcare provider if you have specific conditions or medication interactions to consider.
