Deion Sanders has been dealing with severe foot problems primarily caused by blood clots and poor circulation in his left leg and foot. These circulation issues led to the amputation of two toes (his big toe and second toe) on his left foot in 2021 after he developed femoral arterial blood clots and compartment syndrome, which restricted blood and oxygen flow to the muscles
. He has undergone multiple surgeries-nearly a dozen-to treat persistent blood clotting in his legs and foot, including complex vascular and foot surgeries to remove scar tissue and straighten toes that caused pain and friction
. Despite these efforts, Sanders has experienced ongoing pain, neuropathy (loss of feeling) in the bottom of his foot, and poor circulation, which has put him at risk of further amputation of his left foot
. His medical team has warned that if complications continue, he could lose the entire foot, but as of now, they have opted for surgeries aimed at preserving movement and alleviating pain rather than full amputation
. Sanders has been open about his struggles and remains determined to continue coaching despite his health challenges
. In summary, Deion Sanders' foot problems stem from life-threatening blood clots causing poor circulation, leading to the amputation of two toes and ongoing risk to his left foot, requiring multiple surgeries and careful medical management
