Urea cream is a topical skin medication and moisturizer used primarily to treat dry, rough, thickened, or scaly skin conditions such as eczema, psoriasis, ichthyosis, dermatitis, calluses, corns, and nail problems. It works by softening and hydrating the skin and nails, promoting the shedding of dead skin cells, and improving skin texture
. Key properties and uses:
- Humectant: Urea draws moisture from deeper skin layers and the environment to the outer skin, helping to keep the skin hydrated
- Keratolytic (exfoliating) action: At concentrations above about 10%, urea breaks down keratin proteins in the outer skin layer, which helps remove dead, rough, or scaly skin and smooths thickened areas
- Softens nails: Higher concentrations (above 20%) can soften thickened or damaged nails and assist in non-surgical nail removal
- Enhances absorption: Urea may increase the penetration and effectiveness of other topical medications like corticosteroids and antifungals
Common conditions treated:
- Dry, rough, or scaly skin
- Eczema and dermatitis
- Psoriasis
- Ichthyosis
- Calluses and corns
- Thickened or ingrown nails
- Fungal nail infections and athlete’s foot
Side effects:
- Mild skin irritation, stinging, burning, or itching may occur
- Rarely, allergic reactions with rash, swelling, or breathing difficulty can happen and require medical attention
Availability: Urea creams are available over the counter in various strengths, typically from 5% to 50%, with higher strengths often prescribed for more severe skin conditions
. In summary, urea cream is a safe, effective, and widely used treatment for moisturizing and exfoliating dry, rough, or thickened skin and nails, improving skin barrier function and comfort
