Fluticasone propionate is a medication that belongs to a class of drugs called corticosteroids. It is used to relieve seasonal and year-round allergic and non-allergic nasal symptoms, such as stuffy/runny nose, itching, and sneezing. Fluticasone propionate nasal spray works by blocking the effects of substances that cause allergies (such as pollen, pet dander, dust mites, mold) and reducing swelling in the nose. It can also help relieve allergy eye symptoms such as itchy, watery eyes. Fluticasone propionate is available in different forms for different uses, including creams and ointments for inflammatory skin conditions, inhalers for asthma, and nasal sprays for nasal symptoms. The medication is generally safe, but like all medicines, it can sometimes have side effects, such as an allergic reaction, sudden swelling of the face or tongue, a rash, wheezing, or feeling faint. If you experience any side effects, you should contact your doctor.