Bupropion is primarily used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD), which is a type of depression that occurs at certain times of the year, typically in fall and winter
. It is also widely used as part of smoking cessation programs to help people quit smoking by reducing nicotine cravings and withdrawal symptoms
. Additionally, bupropion is sometimes used off-label for other conditions such as attention-deficit/hyperactivity disorder (ADHD), depression associated with bipolar disorder, and antidepressant-induced sexual dysfunction
. When combined with other medications like naltrexone (as in Contrave), it is used for weight management in certain patients with obesity or overweight conditions
. Bupropion works by influencing brain chemicals, primarily norepinephrine and dopamine, which helps improve mood and reduce cravings
. In summary, the main uses of bupropion are:
- Treatment of major depressive disorder (MDD)
- Treatment and prevention of seasonal affective disorder (SAD)
- Support for smoking cessation
- Off-label uses including ADHD and bipolar depression
- Weight management when combined with other drugs
This makes bupropion a versatile medication in both psychiatric and behavioral health contexts
