what is 70h

3 days ago 6
Nature

70h commonly refers to 7-Hydroxymitragynine (7OH), a highly potent alkaloid found in the kratom plant (Mitragyna speciosa). It is an active metabolite of mitragynine, produced in the liver, and acts primarily on opioid receptors in the brain. 7OH is approximately 13 times more potent than morphine and produces opioid-like effects including potent pain relief, mood enhancement, sedation, and euphoria. It is considered an opioid agonist, with risks of rapid tolerance, physical dependence, and withdrawal symptoms. Recently, there has been increasing concern and regulatory attention due to its potency and health risks, and it is being targeted by authorities for control due to its potential for abuse and serious adverse effects.