Derrick Harmon's mother, Tiffany Saine, passed away late on April 24, 2025, shortly after Derrick was selected by the Pittsburgh Steelers as the 21st overall pick in the NFL Draft. She had been on life support at a hospital in the Detroit suburbs, having endured several brain surgeries and a stroke in recent years that left her paralyzed on her left side. Derrick was able to visit her in the hospital and share the news of his draft selection before she died
. Tiffany Saine had been a significant inspiration and support for Derrick throughout his journey, including his time at Michigan State and later Oregon. Derrick described the moment as bittersweet because his mother had worked just as hard as he did to reach that milestone. The Pittsburgh Steelers organization expressed their condolences and committed to supporting Derrick and his family during this difficult time
