The acronym "TCU" can stand for multiple things depending on the context, but some of the most common meanings include:
- Texas Christian University, a private university in Fort Worth, Texas, established in 1873 and officially named Texas Christian University in 1902
- Transitional Care Unit, a specialized hospital unit designed to help patients transition from acute hospital care to home or rehabilitation
- Transmission Control Unit, a device in automobile transmissions that controls shifting and engine functions
- Teachers Credit Union, a financial cooperative for educators
Other meanings include telecommunication control unit, telematic control unit, Tanzania Commission for Universities, and various other educational institutions and technical terms
. The most widely recognized and primary usage of TCU is Texas Christian University, especially in educational or sports contexts