The typical crossword answers for the clue "pain in the you know what" include:
- HASSLE (6 letters), often used to describe something annoying or troublesome.
- IMPS (4 letters), which appeared in the New York Times Crossword and refers to little devils or troublemakers.
- Other related terms might include BOTHER, NUISANCE, ANNOYANCE, PLAGUE, or PAIN IN THE NECK.
The most likely concise synonym for this clue, especially for a 6-letter answer, is HASSLE. For a 4-letter answer, IMPS is a known solution. If you need the answer for a specific crossword or clue length, please share that detail for a more precise answer. Otherwise, HASSLE and IMPS are the prominent answers for the clue "pain in the you know what."