To decide who to start in an NFL fantasy football lineup for 2025, the top recommended players across key positions are:
- Quarterback: Josh Allen (Buffalo Bills), Lamar Jackson (Baltimore Ravens), and Joe Burrow (Cincinnati Bengals) are excellent top QB choices with high fantasy floors and ceilings.
- Running Back: Jahmyr Gibbs (Detroit Lions), Bijan Robinson (Atlanta Falcons), and Saquon Barkley (Philadelphia Eagles) are the highest-ranked RBs for fantasy due to their strong offensive roles and production.
- Wide Receiver: Ja'Marr Chase (Cincinnati Bengals), Malik Nabers (New York Giants), and Justin Jefferson (Minnesota Vikings) are leading WR options with high target shares and consistent scoring.
- Tight End: Brock Bowers (Las Vegas Raiders), George Kittle (San Francisco 49ers), and Trey McBride (Arizona Cardinals) are top tight ends with strong historical production and potential.
Optimal starters would depend on the position rules of the fantasy format, but generally prioritizing these elite players at their positions sets a strong lineup foundation. For week-to-week decisions, noting matchups and recent performance trends is also key. This advice reflects consensus rankings and expert simulations for the 2025 season as of mid-September 2025.