Hand, foot, and mouth disease (HFM) is contagious mainly during the first week of illness. People infected with HFM are most contagious during the initial 7 to 10 days of symptoms, often even before the rash appears. The contagious period includes the time from a few days before symptoms start, through the symptomatic phase, and can extend for weeks after symptoms have resolved because the virus can remain in bodily fluids such as stool for several weeks to months. The blisters and respiratory droplets are key sources of spreading the virus. Isolation and avoiding contact with others are advised until fever- free for 24 hours and blisters have fully healed, which usually means isolation for about 7 to 10 days. However, even after symptoms disappear, the virus can still be shed and potentially infect others, sometimes for weeks after recovery. In summary:
- Most contagious: First 7-10 days of illness (including days before symptoms start).
- Virus can remain in stool and other secretions for weeks after symptoms resolve.
- Isolation until fever-free for 24 hours and blisters healed (typically 7-10 days).
- Continued hygiene precautions are important to prevent spread even after recovery.
