Antibiotics themselves generally do not delay your period. If your period is delayed after taking antibiotics, it is most often due to the stress and illness that required the antibiotics rather than the antibiotics directly. Such delays are typically no more than 7 to 10 days. Longer delays should prompt a consultation with a healthcare provider. The only antibiotic known to potentially affect menstrual cycles directly is rifampin, which can interfere with hormone levels and menstrual regularity. In normal cases, your menstrual cycle should return to regular once you recover from the illness and stress that accompanied the antibiotic course.