The term that means "affecting the whole of a body or organization" is systemic. This adjective is used to describe something that impacts an entire body or system rather than just a part of it
. In biological and organizational contexts, "systemic" refers to effects or processes that involve the entire system or organism. For example, in the human body, systemic effects involve multiple organs or the whole organism rather than a localized area. This aligns with the concept of levels of organization in the body, where cells form tissues, tissues form organs, organs form organ systems, and organ systems together constitute the whole organism
. Thus, "systemic" precisely captures the idea of something influencing or affecting the entirety of a body or organization.