a student wonders whether removing the nucleus from a cell would result in a new prokaryotic cell. why would this procedure fail to produce a prokaryotic cell?

19 hours ago 1
Nature

Removing the nucleus from a eukaryotic cell would not result in a new prokaryotic cell because the cell would lose essential genetic information and other cellular functions controlled by the nucleus. A prokaryotic cell is fundamentally different from a eukaryotic cell not only because it lacks a nucleus but also because it lacks complex membrane-bound organelles, has a different organization of its DNA (usually a single circular chromosome in the cytoplasm), and structurally and functionally differs in many other ways. Simply removing the nucleus from a eukaryotic cell does not convert its cellular machinery or structure to that of a prokaryote. Specifically, the procedure would fail because:

  • The eukaryotic cell without a nucleus would lack its genetic material, necessary for cell function and survival.
  • Prokaryotic cells have their DNA organized in a nucleoid without a nuclear membrane, unlike the organized chromosomes inside a nucleus.
  • Eukaryotic cells have numerous membrane-bound organelles absent in prokaryotic cells, reflecting a fundamental structural and functional difference.
  • Prokaryotic cells are much smaller and have different cellular processes (like energy production at the cell membrane rather than mitochondria).

Therefore, removing the nucleus from a eukaryotic cell results in a non- functional cell lacking genetic control, not a prokaryotic cell.