The statement "a local reaction is when a chemical enters the bloodstream" is false. A local reaction is a specific reaction observed at the site of exposure to a chemical, such as a burn or rash on the skin where the chemical contacted it. It does not involve the chemical entering the bloodstream. When a chemical enters the bloodstream, it can cause systemic effects, affecting other parts of the body beyond the entry site. Local effects happen right where the chemical makes contact, like skin or eyes, while systemic effects occur when chemicals are absorbed into the bloodstream and distributed through the body, potentially causing harm to organs or tissues distant from the entry point.