The best Daedric artifact to give to Martin in The Elder Scrolls IV: Oblivion during the "Blood of the Daedra" quest is one that is least useful or important to the player's playstyle since whatever artifact is given is permanently lost. Common recommendations include the Sanguine Rose, Volendrung, or the Ring of Khajiiti, as they tend to be less valuable or practical for combat or gameplay compared to others. Notably, the Skeleton Key and Azura's Star are considered too valuable to give away due to their powerful and unique benefits. The Sanguine Rose is particularly popular since it is easy to obtain and its summoned Daedra is not very effective, making it a good choice to sacrifice. Volendrung is cumbersome and not very effective as a weapon, making it another viable option to give to Martin. The Ring of Khajiiti has beneficial but easily replicable enchantments, so it is also a good choice to part with. It is advised never to give Martin artifacts like the Skeleton Key or Azura's Star due to their invaluable utility and permanence in the game.